EPIDEMIOLOGIC CHARACTERISTICS AND IMMUNOLOGICAL ASPECTS OF PRENATAL INFECTION

Epidemiologic and genetic aspects

Epidemiologic and Etiologic Aspects

In the NIH Collaborative Perinatal Project, a prospective study of over 53,000 pregnant women and their offspring, 71 single-born children (13.33/10,000) were found to have a non-syndromal neural tube defect (NTD). A family history was present in only one case. The group of individuals with NTD was compared to a group of 400 randomly selected non-malformed control infants. Of over 50 maternal f...

HPV Infection: Immunological Aspects and Their Utility in Future Therapy

High prevalence and mortality rates of cervical cancer create an imperative need to clarify the uniqueness of HPV (Human Papillomavirus) infection, which serves as the key causative factor in cervical malignancies. Understanding the immunological details and the microenvironment of the infection can be a useful tool for the development of novel therapeutic interventions. Chronic infection and p...

Epidemiologic aspects of leptospirosis.

ADDRESS: Atlanta, Georgia. to a possible source of infection may provide a clue to the recognition of these discases when they occur in children. Rocky Mountain spotted fever, munine typhus and rickettsialpox arc transmitted to children by invertebrate vectors. However, the child frequently may be unaware that he has been the accidental host of vectors of the last two diseases. Since Q fever is...

Hearing loss: A review on molecular genetics and epidemiologic aspects

Background and aims: Hearing loss (HL) happens due to the genetic or environmental causes or both. Risk factors include congenital infections and congenital deformities of auricle and ear duct. The present study was performed to briefly explain the genetics, molecular biology and epidemiology of HL in Middle East especially in Iran. Methods: An intense an...